01043nas a2200229   4500000000100000008004100001260001300042653002900055653001600084653001500100653001200115653001100127653001200138653003100150100001900181245006400200300001000264490000700274050003200281520048600313022001400799       1980                            d  c1980 Apr10aClinical Trials as Topic10aColorimetry10aCreatinine10aDapsone10aHumans10aleprosy10aSpectrometry, Fluorescence1 aBalakrishnan S00aFluorimetric screening of dapsone in urine for drug trials.  a245-80 v52  aInfolep Library - available3 a<p>The DDS/Crestinine ratios obtained by the colorimetric and fluorimetric methods for dapsone were compared in healthy controls, out-patients not claiming to have DDS treatment and inpatients receiving DDS. The ratios by fluorimetric method were considerably lower in the untreated cases compared to the colorimetric method. Fluorimetric assay for dapsone in urine can be more advantageously and reliably used for the preliminary screening of dapsone in urine for drug trials.</p>  a0024-1024