00954nas a2200277   4500000000100000008004100001260001300042653001200055653002300067653000800090653002000098653001200118653001200130653002500142653002500167653001800192100001600210700001800226700001400244245009400258300001100352490000700363050001800370520027400388022001400662       1980                            d  c1980 Jun10aAnimals10aCulture Techniques10aDNA10aGanglia, Spinal10aleprosy10aMitosis10aMycobacterium leprae10aProtein Biosynthesis10aSchwann Cells1 aMukherjee R1 aMahadevan P R1 aAntia N H00aOrganized nerve culture. II. DNA synthesis in Schwann cells in the presence of M. leprae.  a189-920 v48  aMUKHERJEE19903 a<p>Schwann cells that contain M. leprae fail to incorporate DNA precursor, indicating blockage of DNA synthesis. Such a block could lead to no proliferation of Schwann cells, an essential requirement for successful association with axons and consequent myelination.</p>  a0148-916X