01203nas a2200265   4500000000100000008004100001260001300042653001000055653001100065653001200076653000900088653001600097653001200113653002500125653001000150100001100160700001400171700001200185245005500197300000900252490000700261050003200268520062300300022001400923       1981                            d  c1981 Jan10aAdult10aHumans10aleprosy10aMale10aMiddle Aged10aMuscles10aMycobacterium leprae10aThigh1 aKaur S1 aMalik A K1 aKumar B00aPathologic changes in striated muscles in leprosy.  a52-60 v53  aInfolep Library - available3 a<p>Eighteen muscle biopsies from male adult patients of lepromatous and borderline lepromatous leprosy were studied. BI in the biopsies ranged from 1 + to 3+. There was conspicuous absence of granuloma except for a collection of foamy histiocytes in intermysial region and on two occasions in the intermysial nerve endings in LL patients. At places solid staining bacilli were seen in normal looking muscles. None of the biopsies showed loss of muscle striations, fatty change, sarcolemmal changes, fibrosis and necrosis. Hyaline change was seen in two specimens only. Details of these are discussed in this paper.</p>  a0024-1024