01160nas a2200265   4500000000100000008004100001260001300042653001000055653002900065653001100094653002300105653001200128653000900140653001900149100001400168700001500182700001600197700001200213245005800225300001100283490000700294050003200301520054700333022001400880       1981                            d  c1981 Apr10aAdult10aClinical Trials as Topic10aHumans10aLeprostatic Agents10aleprosy10aMale10aPhenylthiourea1 aAnand L C1 aTiwari V D1 aRathore B S1 aSingh O00aClinical trial with CIBA 1906 in lepromatous leprosy.  a278-840 v53  aInfolep Library - available3 a<p>Drug trial with CIBA 1906 was conducted in 50 cases of lepromatous leprosy who were intolerant to dapsone therapy. Drug was tolerated well and lepra reactions were infrequent and mild. Clinical improvement was seen in 72% cases whereas no appreciable change was detected in 28% cases. An average reduction of 0.4 in BI was detected in 62% cases, while remaining cases did not show any reduction in BI. No significant side effects were encountered during the study. Antibacterial activity of CIBA 1906 was not found superior to dapsone.</p>  a0024-1024