01765nas a2200409 4500000000100000008004100001260001300042653001500055653001000070653002000080653001700100653001000117653002800127653001100155653001800166653000900184653001100193653001200204653000900216653001600225653002800241653001500269653002300284653001700307100001400324700001300338700001500351700001500366700001400381700001500395700001600410245006400426300001000490490000700500520083400507022001401341 1982 d c1982 Feb10aAdolescent10aAdult10aBone Resorption10aCarpal Bones10aChild10aDiagnosis, Differential10aFemale10aFoot Diseases10aHand10aHumans10aleprosy10aMale10aMiddle Aged10aNervous System Diseases10aOsteolysis10aRheumatic Diseases10aTarsal Bones1 aQueneau P1 aGabbai A1 aPerpoint B1 aSalque J R1 aLaurent H1 aDecousus H1 aBoucheron S00a[Acro-osteolysis in leprosy. Apropos of 19 personal cases]. a111-90 v493 a

Using their own personal series of 19 cases of leprosy complicated by massive osteolysis (AO), along with a comparison of these cases with data from previously published reports, the authors review the principal clinical and radiological findings of these manifestations which are not observed except in cases of leprosy where neuropathy is present, even though other factors (perforating plantar ulcers, poor hygiene, traumatisms) may play a contributing role independent of possible interference from non specific osteoarthritis or Hansen's bacilla, itself. After reviewing other causes of massive osteolysis and discussing the pathogeny of these manifestations during leprosy, the authors refer to the various therapies which can prevent or stabilize osteolysis or aid the patient to better tolerate its manifestations.

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