01472nas a2200289   4500000000100000008004100001260001300042653001500055653001000070653002100080653002900101653001100130653001100141653001200152653001400164653004000178653002400218653001300242653002700255653001000282100001500292245003500307300000900342490000700351520081000358022001401168       1978                            d  c1978 Jul10aAdolescent10aAdult10aErythema Nodosum10aFalse Positive Reactions10aFemale10aHumans10aleprosy10aPregnancy10aPregnancy Complications, Infectious10aPregnancy, Multiple10aSulfones10aSyphilis Serodiagnosis10aTwins1 aMaurus J N00aHansen's disease in pregnancy.  a22-50 v523 a<p>Hansen's disease with pregnancy is an uncommon concurrence in the United States. The clinical courses of 62 pregnancies in 26 treated patients with various types of Hansen's disease are reported. In general, patients with Hansen's disease do well in pregnancy. However, the subgroups of active lepromatous and dimorphous types have an increased incidence of obstetric and disease complications. Additional important observations include a high incidence of false-positive biologic tests for syphilis, with the possibility that the FTA-ABS test may also be falsely positive in pregnant patients with Hansen's disease. Sulfone drugs may be used safely during pregnancy. There is a low incidence of congenital malformations, but an unusually high incidence of twinning in this small group of patients.</p>  a0029-7844