00939nas a2200253   4500000000100000008004100001260000900042653001800051653001600069653002100085653001100106653001200117653002500129653001600154653000900170100001400179700001500193700001500208245005700223300001000280490000700290520037400297022001400671       1983                            d  c198310aBlood Vessels10aEndothelium10aErythema Nodosum10aHumans10aleprosy10aMicroscopy, Electron10aNeutrophils10aSkin1 aAnthony J1 aVaidya M C1 aDasgupta A00aUltrastructure of skin in erythema nodosum leprosum.  a17-230 v363 a<p>The ultrastructural changes observed in erythema nodosum leprosum lesions were gross damage to blood vessels, particularly the endothelial cells, and deposition of immune complexes in vessel walls. Infiltrating cells and alteration of the ground substance formed a constant feature of the reaction. These changes are characteristic of an immune complex reaction.</p>  a0011-4529