01376nas a2200277   4500000000100000008004100001260001300042653001500055653001000070653002100080653001100101653001700112653001100129653001200140653000900152653001600161100001300177700001400190700001700204245007900221300000900300490000700309050003200316520073600348022001401084       1983                            d  c1983 Jan10aAdolescent10aAdult10aErythema Nodosum10aFemale10aFibrinolysis10aHumans10aleprosy10aMale10aMiddle Aged1 aJain V K1 aVerma K C1 aAggarwal S S00aA study of serum fibrinolytic activity in erythema nodosum leprosum (ENL).  a95-90 v55  aInfolep Library - available3 a<p>Fibrinolytic activity was studied in 31 patients of leprosy and 10 healthy controls. Fibrinolytic activity was found to be significantly decreased in patients with erythema nodosum leprosum, compared to those with uncomplicated lepromatous leprosy, who in turn showed lowered activity compared to patients with tuberculoid form of leprosy and controls. The severity of ENL correlated very well with decrease in fibrinolytic activity. Fibrinolytic activity was improved to levels obtained in uncomplicated lepromatous leprosy after the subsidence of reaction. So it would seem reasonable to suggest that estimation of fibrinolytic activity provides a reliable criteria to quantitate the severity of erythema nodosum leprosum.</p>  a0024-1024