01066nas a2200253   4500000000100000008004100001260001700042653001500059653001000074653001000084653001200094653003100106653001100137653001100148653001200159653000900171653002500180653001300205100001500218245006200233300001000295520049300305022001400798       1982                            d  c1982 Jan-Jun10aAdolescent10aAdult10aChild10aDapsone10aDrug Resistance, Microbial10aFemale10aHumans10aleprosy10aMale10aMycobacterium leprae10aRifampin1 aJanssens L00a[2 cases of paucibacillary leprosy resistant to dapsone].  a181-33 a<p>Two patients are presented with a primary resistant BT leprosy. Diagnosis was made on a clinical base: luck of improvement under supervised sulfone treatment and quick regression of the lesions under a short course of rifampicine (8 weekly doses). The two children lived together with their lepromatous mothers who are suspected of DDS resistance. Where secondary DDS resistance is found only in multibacillary leprosy, primary resistance shows up in all clinical forms of leprosy.</p>  a0001-5938