01387nas a2200301 4500000000100000008004100001260001700042653001200059653002400071653002000095653002800115653001100143653001200154653000900166653002500175653001500200100001500215700001200230700001300242700001300255700001900268700002100287700002400308245009500332300001000427520063400437022001401071 1982 d c1982 Jan-Jun10aAnimals10aAntigens, Bacterial10aCorynebacterium10aHistological Techniques10aHumans10aleprosy10aMice10aMycobacterium leprae10aSkin Tests1 aDelville J1 aSpina A1 aRayyan W1 aCocito C1 aSaint-André P1 aNiamien N'Deli L1 aVan Droogenbroeck J00a[Morphologic and biologic properties of diphtherroid organisms (LDC) isolated in leprosy]. a59-683 a
Acid-alcohol-fast bacteria are not always detectable in all leprosy lesions. Non acid-fast microorganisms may be associated with acid-fast bacteria. The most frequently isolated strains from leprosy lesions are non acid-fast bacteria, morphologically related to C. diptheirae. Hence their designation as diphtheroïds or LDC (leprosy derived corynebacteria). Their antigenic structure is more closely related to M. leprae and other mycobacteria than to classical corynebacteria. This leads to the hypothesis of a potential role in the pathogenesis of leprosy and their use as an antigen for skin tests by leprosy patients.
a0001-5938