01202nas a2200277 4500000000100000008004100001260001300042653001500055653001000070653001100080653001100091653001200102653000900114653001600123653002500139653000900164100001700173700001200190700001300202245013400215300001100349490000700360050003200367520051100399022001400910 1982 d c1982 Apr10aAdolescent10aAdult10aFemale10aHumans10aleprosy10aMale10aMiddle Aged10aMycobacterium leprae10aSkin1 aSrinivasan H1 aRao K S1 aIyer C G00aDiscrepancy in the histopathological features of leprosy lesions in the skin and peripheral nerve. Report of a preliminary study. a275-820 v54 aInfolep Library - available3 a

Simultaneous biopsies of the skin and a cutaneous nerve were done in 36 randomly selected leprosy patients and the histopathological features of the lesion in the two tissues were compared. A discrepancy was noticed in 21 instances. In 19 of these cases the lesions in the nerve were found to be immunologically more deficient and were also bacillated, even when the skin lesion had cleared or regressed. The implications of the findings are discussed and the need for further studies is emphasized.

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