01254nas a2200277   4500000000100000008004100001260001300042653003000055653001200085653001100097653001300108653001200121653001500133653002500148653001900173100001400192700001600206700001500222700001500237245013300252856009000385300001100475490000700486520046900493022001400962       1982                            d  c1982 Aug10aCell Migration Inhibition10aHaptens10aHumans10aLactones10aleprosy10aLeukocytes10aMycobacterium leprae10aTetanus Toxoid1 aFotedar A1 aMustafa A S1 aNarang B S1 aTalwar G P00aImproved leucocyte migration inhibition response of leucocytes from lepromatous leprosy patients with hapten modified M. leprae.  uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1536491/pdf/clinexpimmunol00167-0063.pdf  a317-240 v493 a<p>Two acetoacetylated derivatives of Mycobacterium leprae with variable hapten groups and a conjugate with tetanus toxoid were prepared. These were tested as antigens along with unmodified M. leprae in the leucocyte migration inhibition response of leucocytes from clinically, bacteriologically and histopathologically confirmed cases of lepromatous leprosy. LMI response was poor with M. leprae, but was significantly enhanced with acetoacetylated M. leprae.</p>  a0009-9104