01209nas a2200265   4500000000100000008004100001260001300042653001200055653002500067653001100092653003000103653001200133653004400145653002100189653001500210653001500225653001600240100001200256700001400268245007700282300001000359490000700369520055300376022001400929       1982                            d  c1982 Nov10aDapsone10aDinitrochlorobenzene10aHumans10aHypersensitivity, Delayed10aleprosy10aMacrophage Migration-Inhibitory Factors10aMolecular Weight10aMuramidase10aPrednisone10aThalidomide1 aRea T H1 aYoshida T00aSerum macrophage migration inhibition activity in patients with leprosy.  a336-90 v793 a<p>We have found that 26 of 54 (48%) untreated patients with leprosy had serum migration inhibitory activity, and that this was present in tuberculoid, borderline, and lepromatous forms of the disease. Patients with active recreational states; i.e., reversal reactions, Lucio's reaction, or erythema nodosum leprosum, were particularly apt to have this inhibitory activity. The prevalence of inhibitory activity did not vary significantly with treatment, dinitrochlorobenzene responsiveness, tuberculin responsiveness, or serum lysozyme levels.</p>  a0022-202X