01444nas a2200325 4500000000100000008004100001260001300042653001500055653001000070653001000080653002100090653001100111653001100122653001100133653001200144653000900156653001400165653001000179100001600189700001600205700001600221700001100237700001600248245006200264856004100326300000800367490000700375520072200382022001401104 1983 d c1983 Mar10aAdolescent10aAdult10aChild10aChild, Preschool10aFemale10aHumans10aInfant10aleprosy10aMale10aPhlebitis10aVeins1 aMukherjee A1 aGirdhar B K1 aMalviya G N1 aRamu G1 aDesikan K V00aInvolvement of subcutaneous veins in lepromatous leprosy. uhttp://ila.ilsl.br/pdfs/v51n1a01.pdf a1-60 v513 a
Venous involvement in 31 patients with lepromatous leprosy has been studied in biopsies from clinically involved and clinically normal subcutaneous veins from the forearm. Twenty-nine of these showed histological evidence of leprous phlebitis. The earliest lesion was intimal cell hyperplasia with the presence of acid-fast bacilli in small groups in the intimal cells. This gradually progressed to total occlusion of the vein by lepromatous exudate. The results indicate much greater involvement of veins and possibly other components of the vascular system in patients with lepromatous leprosy than is generally accepted. The importance of such involvement in the pathogenesis of leprosy is also discussed.
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