01375nas a2200241   4500000000100000008004100001260001300042653001700055653003500072653004600107653001100153653001500164653001200179653001400191100001400205700001500219245008300234856004100317300000900358490000700367520074500374022001401119       1983                            d  c1983 Mar10aErythrocytes10aGlucosephosphate Dehydrogenase10aGlucosephosphate Dehydrogenase Deficiency10aHumans10aIsoenzymes10aleprosy10aPhenotype1 aSaoji A M1 aKelkar S S00aErythrocyte glucose-6-phosphate dehydrogenase isoenzyme phenotypes in leprosy.  uhttp://ila.ilsl.br/pdfs/v51n1a07.pdf  a41-40 v513 a<p>Hemolysates from 50 cases of leprosy and five controls were studied for glucose-6-phosphate dehydrogenase (G-6-PD) isoenzyme phenotypes by polyacrylamide disc gel electrophoresis using a miniaturized system. The cases were classified as lepromatous (24), borderline lepromatous (5), borderline tuberculoid (5), and tuberculoid (16) according to the Ridley-Jopling scale. All had been on treatment with dapsone for between two and 12 years. None of the cases showed deficiency of erythrocyte G-6-PD. All the cases and the controls showed the G-6-PD phenotype to be of the B+ variety. Therefore this genetic marker does not appear to be related to susceptibility to leprosy or to the clinical variety of the disease in our situation.</p>
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