01405nas a2200253   4500000000100000008004100001260001300042653001200055653001500067653002300082653001300105653001200118653001400130100001200144700002000156700001600176245008000192856004100272300001100313490000700324050001300331520079300344022001401137       1983                            d  c1983 Sep10aAnimals10aArmadillos10aImmunity, Cellular10aLepromin10aleprosy10aXenarthra1 aJob C K1 aKirchheimer W F1 aSanchez R M00aVariable lepromin response to Mycobacterium leprae in resistant armadillos.  uhttp://ila.ilsl.br/pdfs/v51n3a07.pdf  a347-530 v51  aJOB 19833 a<p>Eight armadillos resistant to the infection of Mycobacterium leprae were lepromin tested. The tissue response was tuberculoid in 5, borderline in 2, and lepromatous in 1, thus showing a wide variation. It is seen that although cell-mediated immunity as evidenced by a tuberculoid granulomatous response to killed M. leprae is associated with resistance to the disease, there may be other yet unknown factors which protect armadillos from the infection. Lepromin responses were recognized histologically even at a low dose of 10(3) organisms, and the response increased with the dose up to 10(7) organisms. The tissue reaction to live organisms was the same as that to killed ones, and autoclaving of M. leprae produced no change in the tissue response to the antigens of M. leprae.</p>  a0148-916X