01239nas a2200289 4500000000100000008004100001260001300042653003300055653001300088653002500101653001100126653000900137653001400146653001200160653000900172653001600181653001100197653001800208653002000226100001400246700001200260245009000272300001000362490000800372520055500380022001400935 1984 d c1984 May10aAnti-Infective Agents, Local10aBandages10aBiological Dressings10aHumans10aIons10aLeg Ulcer10aleprosy10aMale10aMiddle Aged10aSilver10aWound Healing10aWound Infection1 aErsek R A1 aLorio J00aThe most indolent ulcers of the skin treated with porcine xenografts and silver ions. a431-60 v1583 a

Cutaneous ulcers associated with Hansen's disease have long been recognized as among the most indolent of all ulcers. We have successfully treated such ulcers with porcine xenograft, achieving healing in ulcers which had been present for as much as three decades. These results suggest that this regimen may be applicable to other cutaneous ulcers wherever skin is missing. The newly available antibacterial effects of silver-impregnated porcine xenografts should have the result of increasing the effectiveness of the treatment still further.

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