01556nas a2200301   4500000000100000008004100001260001300042653001000055653000900065653001100074653001200085653002000097653001100117653001400128653001200142653000900154653001600163653002700179100001400206700001400220700001700234700001600251245012200267300001000389490000600399520083500405022001401240       1983                            d  c1983 Jun10aAdult10aAged10aFemale10aFingers10aHot Temperature10aHumans10aImmersion10aleprosy10aMale10aMiddle Aged10aSensory Receptor Cells1 aSheskin J1 aSabatto S1 aYosipovitz Z1 aILUKEVICH A00aLack of wrinkle formation in the fingertips of patients with Hansen's disease. Confirmation of previous observations.  a54-600 v83 a<p>Immersion of a hand in water at 38-40 degrees C for half an hour was performed in two phases with a one year interval in 38 patients with Hansen's disease and 20 controls. In all 20 controls wrinkles were produced. However, 32 of the 38 patients failed to show wrinkles in the fingertips. In 12, who participated in both phases, results of the second test confirmed those of the first. This may be an indication of irreversible damage. Due to the small number of individuals tested, no conclusions may be drawn in reference to groups and types of the disease. Provided that these results can be confirmed in larger groups of patients, this method could prove to be a tool in the diagnosis of Hansen's disease. Since the test is very easy to perform, it would be of great value in areas far from specialized medical centers.</p>  a0100-3283