01345nas a2200277   4500000000100000008004100001260001300042653001600055653001500071653001100086653001300097653001200110653001600122653001500138653001600153100001000169700001600179700001600195700001300211245004800224300001000272490000700282050003200289520073200321022001401053       1983                            d  c1983 Jul10aBCG Vaccine10aFoam Cells10aHumans10aLepromin10aleprosy10aLymphocytes10aSkin Tests10aTuberculoma1 aLal S1 aNatarajan S1 aVeliath A J1 aGarg B R00aDoes isopathic phenomenon occur in leprosy?  a495-90 v55  aInfolep Library - available3 a<p>Twenty-five patients of leprosy classified according to the criteria of Ridley and Jopling (1966) were studied to verify the existence of isopathic phenomenon, using lepromin and autoclaved BCG as antigens. BCG as well as lepromin injection sites showed tuberculoid granulomas in all the cases of tuberculoid, borderline tuberculoid, mid-borderline and indeterminate leprosy. In lepromatous and borderline lepromatous cases BCG injection sites showed infiltration of foam cells containing AFB and foci of epithelioid cells, while lepromin injection sites showed infiltration of foam cells containing AFB only. These findings in the present study do not support the occurrence of isopathic phenomenon in leprosy with BCG.</p>  a0024-1024