01264nas a2200349 4500000000100000008004100001260001300042653002500055653001000080653001600090653001200106653003000118653002100148653001100169653001100180653001200191653000900203653001600212653001500228653001300243653000900256653001700265100001500282700001300297700001500310245006300325300001100388490000700399050001600406520047800422022001400900 1983 d c1983 Jul10aAdministration, Oral10aAdult10aClofazimine10aDapsone10aDrug Therapy, Combination10aErythema Nodosum10aFemale10aHumans10aleprosy10aMale10aMiddle Aged10aRecurrence10aSulfates10aZinc10aZinc Sulfate1 aMathur N K1 aBumb R A1 aMangal H N00aOral zinc in recurrent Erythema Nodosum Leprosum reaction. a547-520 v55 aMATHUR 19833 a

Oral zinc sulfate was tried in Eight cases of recurrent Erythema Nodosum Leprosum. To control ENL, they required high dosage of clofazimine and steroids for prolonged periods. After instituting oral zinc, the dose of clofazimine could be reduced to 100 mg twice a week and steroids could be withdrawn completely. Four out of five patients who were not tolerating dapsone earlier, started tolerating dapsone. Incidence and severity of subsequent ENL was also reduced.

 a0024-1024