01100nas a2200241 4500000000100000008004100001260001300042653001200055653001100067653001200078653002300090653002400113100002000137700001200157700001500169700001900184245007200203300001100275490000700286050003200293520051900325022001400844 1983 d c1983 Oct10aDapsone10aHumans10aleprosy10aPatient Compliance10aSelf Administration1 aIrudaya Raj P P1 aLilly L1 aAschhoff M1 aBalakrishnan S00aApplication of "tile reaction" test for screening dapsone in urine. a654-640 v55 aInfolep Library - available3 a
A modified tile reaction test for monitoring self administration of DDS by leprosy patients is described. 385 Urine samples collected at 24 hours after a single dose and at 24, 48 and 72 hours after daily doses of 25, 50, 100 mg were screened for the presence of DDS by this test and the corresponding DDS/C ratios were studied for comparison. Patients compliance was assessed on 268 urine specimens collected on surprise visits. The feasibility of application of this test in field situations is discussed.
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