01723nas a2200229 4500000000100000008004100001260001300042653001200055653001100067653001200078653001200090653002300102653001300125653002400138100001300162245008100175300001000256490000700266050003200273520117400305022001401479 1983 d c1983 Oct10aDapsone10aHumans10aleprosy10aMethods10aPatient Compliance10aPlastics10aSelf Administration1 aNaik S S00aTile test to monitor the self administration of dapsone by leprosy patients. a665-90 v55 aInfolep Library - available3 a

The regularity of attendance of leprosy patients at clinic does not correlate well with regularity in drug consumption. This feature has been reported by several workers from different parts of the world. For monitoring self administration periodical check up of urine for drug content is necessary. The dapsone tile test described by Irudayaraj(1981) is performed in porcalein tile with drop of leprosy patient's urine. An appearance of pink colour and its intensity shows the drug content in urine. Instead of porcalein tile a cheap and readily available plastic blistered capsule card was used which is convenient to carry in the field and is disposable. 184 urine samples were collected in field and tested at field clinic by paramedical workers employing dapsone tile test. The same urine samples were later processed for dapsone/creatinine ratio at the laboratory by photoelectric colorimetric investigations. It was found that the results of dapsone tile test in the field correlated well upto 96% with dapsone/creatinine ratio estimations in the laboratory. The tile test in plastic card is simple to perform under field condition and it is reliable too.

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