01595nas a2200325   4500000000100000008004100001260001300042653001200055653001800067653002300085653001200108653002000120653002600140653001600166653000900182653002500191653001100216653001800227100001600245700001200261700001100273700001600284700002000300245007400320300001000394490000700404050003200411520081200443022001401255       1983                            d  c1983 Jan10aAnimals10aB-Lymphocytes10aImmunity, Cellular10aleprosy10aLeukocyte Count10aLymphocyte Activation10aLymphocytes10aMice10aMice, Inbred Strains10aSpleen10aT-Lymphocytes1 aGanguly N K1 aKumar B1 aKaur S1 aVaishnavi C1 aChakravarti R N00aLymphocyte subpopulations in mice infected with Mycobacterium leprae.  a29-380 v55  aInfolep Library - available3 a<p>T and B cells were quantitated from the spleen of M. leprae infected mice and correlated with bacillary count in the foot pad. Lymphocyte transformation with PHA and M. leprae (armadillo) antigens was also studied during different months of infection. T cell counts dropped gradually but significantly throughout the course of infection. B cells had a concomitant rise up to 6 months and then registered a fall as compared to the initial control figures. Transformation of lymphocytes with PHA fell significantly after 4th month til the end of the experiment, whereas stimulation index for armadillo antigen rose gradually from 3rd month onwards to reach a peak at 6th month and then fell till the end of the experiment with increasing bacterial population whereas B-cell counts showed little change.</p>  a0024-1024