01166nas a2200289   4500000000100000008004100001260000900042653001000051653000900061653002800070653002900098653001100127653001200138653001600150653001400166653002100180100001500201700001300216700001600229700001200245700001400257245010900271300001000380490000800390520046400398022001400862       1983                            d  c198310aAdult10aAged10aAntibodies, Antinuclear10aAntigen-Antibody Complex10aHumans10aleprosy10aMiddle Aged10aPhenotype10aRadioimmunoassay1 aFurukawa F1 aSekita K1 aHamashima Y1 aOzaki M1 aImamura S00aEvaluation of circulating immune complexes and antinuclear antibodies in Japanese patients with leprosy.  a144-60 v2753 a<p>In 79 patients with leprosy a significant increase of anti-extractable nuclear antigen (ENA) antibodies and circulating immune complexes (CIC) was found. No correlation between CIC and anti-ENA antibodies was demonstrable. Since such a correlation is known from antinuclear antibodies and CIC in patients with systemic lupus erythematosus, it appears likely that anti-ENA antibodies do not play a causative role in CIC-mediated pathogenesis of leprosy.</p>  a0340-3696