01542nas a2200373   4500000000100000008004100001260001300042653001000055653001500065653001100080653001100091653001200102653000900114653001600123653001700139653001400156653001500170653003200185653003000217653003000247100001300277700001200290700001600302700002000318700001300338700001400351245010200365856005900467300000900526490000700535050001500542520059700557022001401154       1999                            d  c1999 Mar10aAdult10aBiomarkers10aFemale10aHumans10aleprosy10aMale10aMiddle Aged10aNitric Oxide10aPrognosis10aRecurrence10aSensitivity and Specificity10aSeverity of Illness Index10aStatistics, Nonparametric1 aSchön T1 aGebre N1 aSundqvist T1 aHabetmariam H S1 aEngeda T1 aBritton S00aIncreased levels of nitric oxide metabolites in urine from leprosy patients in reversal reaction.  uhttp://leprev.ilsl.br/pdfs/1999/v70n1/pdf/v70n1a11.pdf  a52-50 v70  aSCHON 19993 a<p>We measured the metabolites of NO [nitrite (NO2-) and nitrate (NO3-)] in urine from Ethiopian patients suffering from leprosy. The urinary level of NO2-/NO3- in a group of healthy Ethiopians was 1020 +/- 471 microM (n = 22). Leprosy patients in reversal reaction had significantly higher levels of NO2-/NO3- (1817 +/- 492 microM, p < 0.001, n = 12) than both the control group and leprosy patients who were not in reversal reaction (1079 +/- 446 microM, n = 12). We conclude that the reversal reaction in leprosy in associated with increased urinary levels of nitric oxide metabolites.</p>  a0305-7518