01527nas a2200253   4500000000100000008004100001260001700042653002600059653002000085653001100105653002400116653001200140653001800152653002500170100001200195700001800207700001700225700001600242245009900258300001100357490000900368520088200377022001401259       1984                            d  c1984 Nov-Dec10aAnti-Bacterial Agents10aCorynebacterium10aHumans10aIn Vitro Techniques10aleprosy10aStearic Acids10aTerminology as Topic1 aBrown S1 aLanéelle M A1 aAsselineau J1 aBarksdale L00aDescription of Corynebacterium tuberculostearicum sp. nov., a leprosy-derived Corynebacterium.  a251-670 v135B3 a<p>Leprosy-derived corynebacteria (LDC) have been extensively studied over the past decade. A composite of their biological properties (cell morphology, staining reactions, cellular inclusions and guanine-plus-cytosine content of their deoxyribonucleic acid; 16 strains studied) and their chemical structures (peptidoglycan type, major cell wall polysaccharide, major glycolipid as well as characteristic mycolic acids) appears to define them as members of the genus Corynebacterium. In relation to other corynebacteria found in humans, including "JK corynebacteria", they seem to be distinct. They are here named Corynebacterium tuberculostearicum sp. nov. because they produce a 10-methyloctadecanoic (tuberculostearic) acid (8 strains studied). This and some of their other attributes are considered in relation to properties of leprosy bacilli and Mycobacterium leprae.</p>  a0300-5410