01220nas a2200193 4500000000100000008004100001260001700042653001200059653003100071653002300102653003200125653002500157100001500182245015000197300001000347490000600357520064900363022001401012 1983 d c1983 Jan-Mar10aDapsone10aDrug Resistance, Microbial10aLeprostatic Agents10aMicrobial Sensitivity Tests10aMycobacterium leprae1 aPattyn S R00aMouse foot pad technique for evaluation of drug resistance of M. leprae and other laboratory techniques to be used in leprosy control programmes. a29-320 v13 a
There is no need for mouse foot pad facilities for drug sensitivity testing to start leprosy control programmes, since the size of the problem is known. There will however be a need for some mouse foot pad work in later stages, to document relapse cases and test relapse strains for drug sensitivity. Arrangements should be made to ship such specimens to existing laboratories. There is more need however for facilities for monitoring drug intake. Finally, where nonexistant, there may be incidentally some need for quality control of imported drugs, which can be solved through collaboration with existing facilities in other countries.
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