01467nas a2200253   4500000000100000008004100001260001700042653002700059653002400086653002000110653003800130653001100168653001200179653002400191653002500215100001300240700001600253700001400269245009000283300001000373490000600383520081000389022001401199       1984                            d  c1984 Oct-Dec10aAntibodies, Monoclonal10aAntigens, Bacterial10aCorynebacterium10aEnzyme-Linked Immunosorbent Assay10aHumans10aleprosy10aMycobacterium bovis10aMycobacterium leprae1 aPapa F P1 aRauzier J Y1 aDavid H L00aOccurrence of antigen BCG 60 in leprosy derived corynebacteria and other coryneforms.  a351-80 v23 a<p>Previous studies have shown that anti BCG 60 monoclonal antibody could recognize major antigen A 7 of M. leprae. In the present investigation we attempted to search the presence of the same antigen from the strains of Leprosy Derived Corynebacteria (LDC+), which were isolated from leprosy lesions and were supposed to be the cultivable form of the leprosy bacillus. A comparative study was equally performed on 7 strains of Corynebacteria which were isolated in France and had no relation with leprosy patients (LDC-). Utilizing the ELISA technique with an anti BCG 60 monoclonal antibody, it was found that all the three LDC+ strains contained an antigenic determinant common to M. leprae, however no LDC+ specificity was found as this antigenic determinant was also revealed on two LDC- strains.</p>  a0001-5938