01478nas a2200349 4500000000100000008004100001260001300042653001500055653001000070653002100080653001100101653001400112653001100126653001200137653001500149653001000164653000900174653001600183653002500199653001100224100001400235700001400249700001400263700001400277700001600291245007300307300001000380490000700390050003200397520068500429022001401114 1983 d c1983 Jul10aAdolescent10aAdult10aErythema Nodosum10aFemale10aGranuloma10aHumans10aleprosy10aLeukocytes10aLiver10aMale10aMiddle Aged10aMycobacterium leprae10aSepsis1 aZawar P B1 aHolla V V1 aPatil S M1 aZawar M P1 aChawhan R N00aBacillaemia in lepra reaction: its correlation with liver pathology. a570-50 v55 aInfolep Library - available3 a
Thirty patients of lepromatous leprosy in a state of reaction (ENL) were studied for bacillaemia and a correlation was made with liver pathology. Buffy coat smears were examined in all, eliminating as far as possible the chances of contamination of blood by the skin bacilli. Thirteen out of thirty patients showed presence of acid fast bacilli (AFB) in the buffy coat smear. Hepatic involvement in the form of leprous granuloma was observed in all, of which 93.3% showed presence of AFB. It is concluded that during reaction the possibility of heightened bacillaemia is less likely and that the systemic spread of infection is not accentuated during the bouts of reaction.
a0024-1024