01396nas a2200361   4500000000100000008004100001260001300042653001500055653001000070653002300080653001000103653002100113653001400134653001100148653001300159653001200172653001600184653000900200653001600209653002500225653000900250653001600259100001500275700001800290700001400308700001200322245012300334856004100457300001100498490000700509520050400516022001401020       1983                            d  c1983 Dec10aAdolescent10aAdult10aBacterial Vaccines10aChild10aErythema Nodosum10aGranuloma10aHumans10aLepromin10aleprosy10aLymphocytes10aMale10aMiddle Aged10aMycobacterium leprae10aSkin10aVaccination1 aBhatki W S1 aChulawala R G1 aBAPAT C V1 aDeo M G00aReversal reaction in lepromatous patients induced by a vaccine containing killed ICRC bacilli--a report of five cases.  uhttp://ila.ilsl.br/pdfs/v51n4a02.pdf  a466-720 v513 a<p>Clinico-pathological features of five cases of lepromatous leprosy exhibiting "reversal" reaction with upgrading of lesions following vaccination with ICRC vaccine have been described. Two patients also developed ENL. Associated with the "reversal" reaction, the patients exhibited lepromin conversion. No evidence of fresh nerve lesions was observed in any patient. Besides lepromin conversion, occurrence of "reversal" reaction is yet another evidence of immunogenicity of the ICRC vaccine.</p>  a0148-916X