01369nas a2200313   4500000000100000008004100001260001300042653001200055653001200067653003100079653001100110653002500121653001200146653000900158653002500167653002600192100001900218700001700237700001500254700002400269700001900293700001500312245010400327300000900431490000700440050003200447520056200479022001401041       1983                            d  c1983 Jan10aAnimals10aDapsone10aDrug Resistance, Microbial10aHumans10aInstitutionalization10aleprosy10aMice10aMycobacterium leprae10aRetrospective Studies1 aBalakrishnan S1 aSeshadri P S1 aNeelan P N1 aVenkataramaniah H N1 aHarikrishnan S1 aBhatia V N00aStudies on sulphone resistant strains of M. leprae in field and institutionalized cases of leprosy.  a71-50 v55  aInfolep Library - available3 a<p>The proportions of dapsone resistant strains of M. leprae in cases from the field and in patient institutionalized for treatment were compared. Identification of dapsone resistance was done by mouse-foot-pad experiments carried out in the Laboratory in Central Leprosy Teaching and Research Institute, Chengalpattu. A higher percentage of resistance was detected among institutional patients as compared to field cases. The distribution of M.I. ranges of M. leprae in dapsone resistant subjects was not different from that in dapsone sensitive cases.</p>  a0024-1024