01296nas a2200301   4500000000100000008004100001260001600042653001200058653001300070653001100083653003500094653001400129653002300143653000900166653002500175653002900200653003100229653002400260100001200284700001200296700001000308700001200318245016200330300001200492490000700504520046900511022001400980       1983                            d  c1983 Aug 1510aAnimals10aCollagen10aFibrin10aFluorescent Antibody Technique10aGranuloma10aImmunity, Cellular10aMice10aMice, Inbred Strains10aMycobacterium Infections10aMycobacterium lepraemurium10aSpecies Specificity1 aSatoh M1 aIzaki S1 aKon S1 aIzaki M00aFibrin and collagen deposition and fibroblasts proliferation in granuloma of murine leprosy. Comparison of two mouse strains with different immune reactions.  a899-9020 v393 a<p>Comparative immunofluorescence study with murine lepromas induced in C57BL/6NJcl (immunologically high responder) and CBA/N (low responder) mouse strains revealed that fibrin formation was associated with cell-mediated immune resistance against invasive bacilli. Histochemistry on paraffin sections further elucidated fibroblast proliferation and formation of collagen fibers following fibrin deposition only in murine lepromas with positive host reactions.</p>  a0014-4754