01138nas a2200217   4500000000100000008004100001260001600042653003800058653001600096653001100112653001200123653002500135653002000160100001400180700001700194245008800211300001100299490000800310520058800318022001400906       1983                            d  c1983 Sep 0910aEnzyme-Linked Immunosorbent Assay10aGlycolipids10aHumans10aleprosy10aMycobacterium leprae10aSerologic Tests1 aYoung D B1 aBuchanan T M00aA serological test for leprosy with a glycolipid specific for Mycobacterium leprae.  a1057-90 v2213 a<p>A phenolic glycolipid from Mycobacterium leprae was purified and used as antigen in an enzyme-linked immunosorbent assay. Antibodies directed against the lipid were seen in serums from leprosy patients but not in serums from uninfected controls or patients infected with other mycobacteria, including Mycobacterium tuberculosis. The antibody response distinguished between the Mycobacterium leprae lipid and the structurally related phenolic glycolipid from Mycobacterium kansasii. This assay has considerable potential as a specific serodiagnostic test for leprosy infection.</p>  a0036-8075