01405nas a2200325   4500000000100000008004100001260001300042653001500055653001000070653000900080653001000089653001100099653001400110653001100124653001200135653000900147653001600156653000900172653001800181100001400199700001400213700001300227700001500240245008800255300001100343490000700354050001600361520068800377022001401065       1984                            d  c1984 Sep10aAdolescent10aAdult10aAged10aChild10aFemale10aGranuloma10aHumans10aleprosy10aMale10aMiddle Aged10aSkin10aT-Lymphocytes1 aWallach D1 aFlageul B1 aBach M A1 aCottenot F00aThe cellular content of dermal leprous granulomas: an immuno-histological approach.  a318-260 v52  aWALLACH19843 a<p>An indirect immunofluorescence technique with monoclonal antibodies has been used to identify T cells, T helper cells, T suppressor cells, and granulocytes in the dermal granulomas of 22 patients with leprosy. In tuberculoid leprosy, T helper cells predominated and T suppressor cells were located at the periphery of well-circumscribed granulomas. In lepromatous leprosy, the two subsets of T cells were numerous in treated patients. In ENL lesions, T cells were more numerous and T helper cells predominated. Enumerations of the T cell subsets in the dermis and in the blood showed similar changes, but these changes were quantitatively more marked in the dermal granulomas.</p>  a0148-916X