01445nas a2200289 4500000000100000008004100001260001700042653001800059653002200077653001100099653001200110653002000122653002200142653001800164100001400182700001100196700001600207700001200223700001300235700001500248245011700263300001100380490000700391050003200398520071100430022001401141 1984 d c1984 Oct-Dec10aCulture Media10aGrowth Substances10aHumans10aleprosy10aLeukocyte Count10aRosette Formation10aT-Lymphocytes1 aPatil S A1 aRamu G1 aDwivedi P D1 aSinha S1 aGhei S K1 aSengupta U00aEffect of leprosy sera and foetal calf serum (FCS) on the T cell number of peripheral blood of leprosy patients. a784-910 v56 aInfolep Library - available3 a
Study was conducted in 24 cases of various types of leprosy and 10 healthy controls to find out the effect of various sera on the T cell count of peripheral blood lymphocytes by sheep erythrocyte rosetting method. The percentage of T lymphocytes in lepromatous and tuberculoid cases were significantly lower compared to that in normal healthy controls. All sera except FCS had a stimulatory effect on the number of T cells. The cells incubated for 24 hours in FCS did not show any stimulatory effect on the number of T cells, however, these FCS incubated cells showed a significant elevation in the number of T cells when further incubated in sera either from leprosy cases or from healthy subjects.
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