01229nas a2200253   4500000000100000008004100001260001300042653001100055653002300066653001200089653001800101653002800119100001400147700001300161700001600174700001500190700001400205700001300219245009400232300001200326490000700338520061600345022001400961       1984                            d  c1984 Dec10aHumans10aLeprostatic Agents10aleprosy10aT-Lymphocytes10aTuberculosis, Cutaneous1 aSarno E N1 aKaplan G1 aAlvaranga F1 aNogueira N1 aPorto J A1 aCohn Z A00aEffect of treatment on the cellular composition of cutaneous lesions in leprosy patients.  a496-5000 v523 a<p>We report on the cellular composition of the cutaneous lesions of 38 leprosy patients prior to and after 12-18 months of chemotherapy. All of the patients with tuberculoid (TT) disease had OKT4/OKT8 ratios that exceeded 1.0. In the indeterminate patients, the ratio varied depending upon the immune status of the individual. A low ratio of OKT4/OKT8 cells (0.25) was found in the LL patients as previously reported. The low ratio of OKT4/OKT8 in the lesions of lepromatous patients did not undergo significant changes after treatment in spite of a marked reduction in the number of intracellular bacilli.</p>  a0148-916X