01145nas a2200301 4500000000100000008004100001260001300042653001000055653002700065653001100092653001100103653002100114653001200135653000900147653001600156653001800172100001200190700001200202700001300214700001300227700001100240700001100251245008100262300001000343490000700353520046900360022001400829 1984 d c1984 Dec10aAdult10aAntibodies, Monoclonal10aFemale10aHumans10aLangerhans Cells10aleprosy10aMale10aMiddle Aged10aT-Lymphocytes1 aLiu J H1 aShi Y F1 aKong Q Y1 aYang L H1 aLi W Z1 aYe G Y00aObservations of Langerhans' cells in leprosy using monoclonal antibody OKT6. a524-60 v523 a
Changes in the Langerhans' cells (LC) in seven cases of leprosy were observed using the monoclonal antibody OKT6. In the epidermis of the lesions of most of the leprosy cases, the processes of LC were reduced or diminished. Some LC were disintegrated. In two BT cases in the upgrading (type 1) reactional stage, either increased numbers and aggregation of OKT6-positive cells in clusters or their disintegration was seen in different areas of the epidermis.
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