01434nas a2200289   4500000000100000008004100001260001300042653001600055653001200071653002000083653003000103653001100133653001200144653000900156653001300165653001100178653001800189100001100207700001500218700001600233245004800249300001000297490000700307050003200314520078400346022001401130       1981                            d  c1981 Apr10aClofazimine10aDapsone10aDrug Evaluation10aDrug Therapy, Combination10aHumans10aleprosy10aMale10aRifampin10aSepsis10aThioacetazone1 aRamu G1 aSengupta U1 aDesikan K V00aEvaluation of multiple regimens in leprosy.  a190-60 v53  aInfolep Library - available3 a<p>Assessment of bacteraemia has been made at weekly intervals in 36 lepromatous leprosy patients who were put on different antileprosy drug under four regimens, viz., DDS alone, DDS in combination with rifampicin (DDS + RIF), clofazimine (DDS + CLF) and thiacetazone (DDS + TCT). In general, with the continuation of treatment the bacillary load in the blood decreased considerably while bacteriological index (BI) of the skin remained constant during the study. No significant difference was noted in M. leprae clearance from blood between the groups treated with DDS alone and groups treated in combination with CLF and TCT. However, DDS + RIF treatment was most efficient in clearing acid-fast bacilli (AFB) from blood as compared to those noted with other drug regimens.</p>  a0024-1024