01506nas a2200349 4500000000100000008004100001260001300042653001500055653001000070653001000080653001600090653001200106653003000118653001100148653001100159653001400170653001200184653000900196653001600205653001300221653001800234100001400252700001200266700001200278700001600290245015900306300001100465490000700476050003200483520062700515022001401142 1981 d c1981 Apr10aAdolescent10aAdult10aChild10aClofazimine10aDapsone10aDrug Therapy, Combination10aFemale10aHumans10aIsoniazid10aleprosy10aMale10aMiddle Aged10aRifampin10aThioacetazone1 aKundu S K1 aGhosh S1 aHazra S1 aChaudhury S00aMultiple drug therapy--a comparative study with 2 tier and 3 tier combination of rifampicin, clofazimine, DDS, INAH and thiacetazone in lepromatous cases. a248-580 v53 aInfolep Library - available3 a

A comparative study with 2 tier and 3 tier combination of Rifampicin, Clofazimine, DDS, INAH and Thiacetazone was conducted on fifty lepromatous leprosy cases for varying periods. Assessment showed that 2 tier combination of clofazimine and DDS produced good results but the cost stood in the way; whereas 3 tier combination of DDS, thiacetazone and INAH also yielded good results with much less expenses to be incurred by the patients. Whether therapy with this 3 tier combination could be continued for a longer period with sustained improvement is yet to be assessed by further studies for a considerable period.

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