01497nas a2200337   4500000000100000008004100001260001700042653001500059653001000074653000900084653001800093653001100111653001100122653002100133653002100154653002100175653002000196653001200216653000900228653001600237653001000253100001100263700001400274700002000288700001200308245005100320300001100371490000700382520075600389022001401145       1977                            d  c1977 Oct-Dec10aAdolescent10aAdult10aAged10aAqueous Humor10aFemale10aHumans10aImmunoglobulin A10aImmunoglobulin G10aImmunoglobulin M10aImmunoglobulins10aleprosy10aMale10aMiddle Aged10aTears1 aSaha K1 aSarin G S1 aChakraborty A K1 aSen D K00aOcular immunoglobulins in lepromatous leprosy.  a338-420 v453 a<p>Immunoglobulin levels in the ocular fluids have been estimated in normal subjects and lepromatous leprosy patients. In the normal tear, IgA is the major immunoglobulin while IgG is the only immunoglobulin detected in the aqueous humor. The immunoglobulin profiles in the tear and the aqueous humor in normal subjects are different. The mean IgA level in the tears of the lepromatous leprosy group is significantly lower than in the control patients. IgA and IgG levels are raised in the aqueous humor of some leprosy cases who had suffered from uveitis in the past and also in all cases with active endogenous uveitis. Therefore, in lepromatous leprosy the pattern of immunoglobulin alteration in the tear and the aqueous humor is not parallel.</p>  a0148-916X