01171nas a2200265 4500000000100000008004100001260001700042653001500059653001000074653001100084653001800095653001200113653001000125653000900135653001300144100001500157700001900172700001100191700001300202245006600215300000900281490000700290520059400297022001400891 1978 d c1978 Jan-Mar10aAdolescent10aChild10aHumans10aKupffer Cells10aleprosy10aLiver10aMale10aNecrosis1 aMittal M M1 aMaheshwari H B1 aSaha K1 aSharma R00aHepatic lesions in asymptomatic children of leprosy patients. a42-60 v463 a
Forty-two asymptomatic children of leprosy patients were studied for possible hepatic lesions. Hepatic lesions were observed in 47% while acid-fast bacilli in the liver were found in 9.5%. The most frequent lesions encountered included granuloma in 9.5%, focal areas of necrosis in 14%, portal triaditis in 17%, and Kupffer cell hyperplasia in 33%. Occasionally more than one lesion was observed in a biopsy. No correlation with the occurrence of the various hepatic lesions could be made with a history of BCG vaccination or results of skin tests done with tuberculin and lepromin.
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