01113nas a2200241   4500000000100000008004100001260001300042653001200055653002700067653001200094653000900106653002300115653001800138100001200156700001300168700001400181245006600195300000900261490000700270050003200277520054800309022001400857       1976                            d  c1976 Jan10aAnimals10aDisease Models, Animal10aleprosy10aMice10aNerve Degeneration10aSciatic Nerve1 aMehta L1 aShetty V1 aAntia N H00aStudy of early nerve lesions in mice infected with M. leprae.  a31-50 v48  aInfolep Library - available3 a<p>The present study is of quantitative histology in immunologically intact mice inoculated with M. leprae. Total twelve sciatic nerves are studied. The fibres are grouped as large, medium and small sized fibres. Initially there is loss of small size fibres. At later stages there is involvement of all sized fibres and ultimately Wallerian type of degeneration sets in. The process of regeneration is more active than that of human leprosy of tuberculoid type. This study adds a new dimension in understanding the pathogenesis of leprosy.</p>  a0024-1024