01084nas a2200193   4500000000100000008004100001260001300042653001600055653001200071653001200083653001700095100001900112245005700131300001100188490000700199050003200206520063800238022001400876       1976                            d  c1976 Oct10aAmino Acids10aEnzymes10aleprosy10aMucoproteins1 aBalakrishnan S00aBiochemical aspects of reactional states in leprosy.  a406-120 v48  aInfolep Library - available3 a<p>Sequential biochemical investigations conducted in cases of lepromatous leprosy in the reactive as well as subsided phases indicated elevated serum levels of mucoproteins and sialic acids and skin levels of hydroxy-proline and hexosamine in the reactive phase of lepromatous leprosy. Elevation of the urinary excretion of hydroxy-proline and certain other amino acids was also noticed during 'lepra reaction'. Enhancement of serum levels of Aldolase, CPK, LDH and transaminases was observed in the reactive phase of lepromatous leprosy. These findings taken as a whole suggest a generalised tissue breakdown in lepra reaction.</p>  a0024-1024