01168nas a2200277   4500000000100000008004100001260001300042653002000055653001800075653001100093653001200104653001200116653002500128653002200153653001400175100001200189700001200201700001500213700001300228700001600241245007200257300001200329490000800341520052700349022001400876       1969                            d  c1969 Nov10aCorynebacterium10aCulture Media10aHumans10aleprosy10aMethods10aMicroscopy, Electron10aOsmotic Fragility10aPhenotype1 aFreer J1 aKim K S1 aKrauss M R1 aBeaman L1 aBarksdale L00aUltrastructural changes in bacteria isolated from cases of leprosy.  a1062-750 v1003 a<p>One of two groups of rod-shaped bacteria (bacilli) isolated from cases of human leprosy have been found, under certain cultural conditions, to give rise to unusual phenotypes. In electron micrographs of ultrathin sections and negatively stained whole cells of these osmotically fragile bacteria, ultrastructural anomalies are apparent and seem to arise from disorder in the process(es) of septum formation or cell envelope biosynthesis or both. Two of the four strains examined are related to Corynebacterium acnes.</p>  a0021-9193