01645nas a2200313 4500000000100000008004100001260001300042653001500055653001000070653001000080653002100090653001100111653001100122653001100133653001300144653001200157653000900169653001600178100001400194700001200208700001400220700001600234245009300250300001100343490000700354050003200361520092400393022001401317 1979 d c1979 Oct10aAdolescent10aAdult10aChild10aChild, Preschool10aFemale10aHumans10aInfant10aLepromin10aleprosy10aMale10aMiddle Aged1 aKundu S K1 aGhosh S1 aHazra S K1 aChaudhury S00aNature and familial character of lepromin sensitivity in 27 families and their siblings. a465-740 v51 aInfolep Library - available3 a

A group of 27 families consisting of 176 individuals had been investigated for the lepromin sensitivity (with Dharmendra antigen). The families were arranged under group A (9 families) in whom either of the parents or both were suffering from Lepromatous type of leprosy, group B numbering 4 families, of whom either of the parents or both were suffering from non-lepromatous type of leprosy and group C comprising 14 families where none of the parents was suffering from leprosy but some of the each family had the disease in their siblings. The present study points towards the possible genetic influence on lepromin sensitivity but at times may be influenced by the environmental factors. However the study does not permit to reach any valid conclusions; further elaborate investigations alone could prove the useful role of genetic influence in the propagation of lepromin sensitivity to the subsequent sibs.

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