01172nas a2200277   4500000000100000008004100001260001300042653001500055653001000070653001200080653003200092653001100124653001100135653003000146653001200176653000900188653001600197100001400213700001600227245009500243300001100338490000700349050003200356520049200388022001400880       1979                            d  c1979 Jul10aAcedapsone10aAdult10aDapsone10aDelayed-Action Preparations10aFemale10aHumans10aInjections, Intramuscular10aleprosy10aMale10aMiddle Aged1 aAnand L C1 aRathore B S00aActivity and effective serum level of repository sulphones (DADDS) in lepromatous leprosy.  a358-620 v51  aInfolep Library - available3 a<p>35 cases of lepromatous leprosy were studied to evaluate the effective blood level and long depot action of acedapsone (DADDS). It was revealed that serum level of this drug is maintained well above the minimum inhibitory concentration upto 60 days following single intramuscular injection. No significant untoward effects of the drug were encountered except one case of Erythema Nodosum Leprosum and six patients with mild reactional symptoms in the form of fever and arthralgia.</p>  a0024-1024