01706nas a2200301   4500000000100000008004100001260001700042653001000059653004000069653001100109653001500120653002800135653001200163653000900175653001600184653002100200653001000221100001600231700001400247700001400261700001600275245006800291300001000359490000700369050003200376520098200408022001401390       1998                            d  c1998 Oct-Dec10aAdult10aElectrophoresis, Polyacrylamide Gel10aHumans10aIsoenzymes10aL-Lactate Dehydrogenase10aleprosy10aMale10aMiddle Aged10aReference Values10aSemen1 aSirmour S K1 aVerma P K1 aSingh J N1 aOkhandiar P00aLDH isozymes with anomalous bands in semen of leprosy patients.  a405-90 v70  aInfolep Library - available3 a<p>Activity of LDH isozymes was evaluated electrophoretically on 7% acrylamide gel in semen of 37 leprosy patients (15 with borderline, 12 with borderline tuberculoid and ten with lepromatous leprosy) and ten fertile men of 30-45 years of age. Significantly lower activities were recorded of LDH1 in all categories of leprosy patients. Similarly, lowering of LDH2 activity was noticed in borderline and lepromatous cases only, lowering of LDH4 activity in lepromatous cases only and LDH5 activity was lowered in borderline leprosy patients. Lowest activity of LDH3 and absence of LDHx were found in lepromatous leprosy. However, in borderline tuberculoid patients, LDH3 and LDHx were significantly higher. This exceptional increase in activity was found to be due to presence of additional (anomalous) isozymes bands of LDH3, LDHx and LDH4 in 25% of borderline tuberculoid patients. Additional bands of LDH3 have also been located in 40% of the borderline leprosy patients.</p>  a0254-9395