01855nas a2200373   4500000000100000008004100001260001300042653001500055653001000070653000900080653001100089653001400100653001800114653001100132653001100143653001200154653002400166653002500190653000900215653001600224653002400240653003100264100001700295700001400312700001300326700001500339700001600354700001000370245006600380300001200446490000800458520100100466022001401467       1998                            d  c1998 Nov10aAdolescent10aAdult10aAged10aBiopsy10aEndoscopy10aEthmoid Sinus10aFemale10aHumans10aleprosy10aLeprosy, Borderline10aLeprosy, lepromatous10aMale10aMiddle Aged10aProspective Studies10aTomography, X-Ray Computed1 aSrinivasan S1 aNehru V I1 aMann S B1 aSharma V K1 aBapuraj J R1 aDas A00aStudy of ethmoid sinus involvement in multibacillary leprosy.  a1038-410 v1123 a<p>The nasal mucosal involvement in lepromatous leprosy is well recognized. Currently interest has centred around the involvement of paranasal sinuses in leprosy. They act as a reservoir and constant source of reinfection to the nasal mucosa. In the present prospective study 25 untreated patients with multi-bacillary leprosy were included. Clinical examination, computed tomography (CT) scan of paranasal sinuses, ethmoid sinus endoscopy and biopsy were carried out in all patients, to investigate the involvement of the paranasal sinuses in leprosy. Ethmoid sinus involvement was noted in 20 patients on CT scan. Bilateral involvement was more common (65 per cent). Anterior ethmoids were more commonly affected (65 per cent). On ethmoid sinus endoscopy abnormal mucosa was noted in 17 patients (68 per cent). Ethmoid sinus biopsy was confirmative in 16 patients (64 per cent). Statistically significant correlation was found between CT findings, sinus endoscopy and sinus biopsy findings.</p>  a0022-2151