01125nas a2200277   4500000000100000008004100001260001300042653001000055653001100065653001100076653001200087653000900099653001600108653002500124653002200149653002400171653004000195653001800235653000900253100001400262245003500276300001000311490000700321520050500328022001400833       1971                            d  c1971 Dec10aAdult10aFemale10aHumans10aleprosy10aMale10aMiddle Aged10aMycobacterium leprae10aNeural Conduction10aNeurofibromatosis 110aPeripheral Nervous System Neoplasms10aSchwann Cells10aSkin1 aSwift T R00aNeurofibromatosis and leprosy.  a743-90 v343 a<p>Two patients with neurofibromatosis and leprosy are reported. Both had active lepromatous leprosy and generalized neurofibromata. The bacilli appear in huge numbers within the cytoplasm of the cells making up the neurofibromata, which become distended and resemble lepra cells. Since these cells are believed to derive from Schwann cells, the findings in these patients support the idea that leprosy affects nerves initially by proliferating in Schwann cells and producing changes within them.</p>  a0022-3050