01188nas a2200229 4500000000100000008004100001260001300042653002800055653002900083653001100112653002100123653001200144653001300156653002700169100001500196700001800211245009400229300001000323490000700333520060400340022001400944 1972 d c1972 Sep10aDiagnosis, Differential10aFalse Positive Reactions10aHumans10aImmunoglobulin E10aleprosy10aSyphilis10aSyphilis Serodiagnosis1 aGarner M F1 aBackhouse J L00aThe rapid plasma reagin (circle) card test in biological false positive and leprosy sera. a786-80 v253 a

The rapid plasma reagin (RPR) circle card and the Venereal Disease Reference Laboratory (VDRL) slide test results were compared on a group of sera known to show biological false positive (BFP) reactions to reagin detection tests for syphilis. The RPR test was more specific than the VDRL test on the sera selected, ie, it gave fewer false positive results than the VDRL test. However, in a group of presumed normal sera, the RPR test gave BFP reactions while the VDRL test gave none. The RPR test gave fewer BFP reactions than the VDRL test in 269 sera from patients with lepromatous leprosy.

 a0021-9746